Equine Pregnancy Laboratory - Selected Publications
Shilton, CA; Kahler, A; Crabtree, JR; Crowhurst, J; Davis, BW; McGladdery, AJ; Wathes, DC; Raudsepp, T; de Mestre, Whole genome analysis reveals aneuploidies in early pregnancy loss in the horse., Scientific Reports. 2020 Aug 7;10(1):13314. doi: 10.1038/s41598-020-69967-z. Free access at https://www.nature.com/articles/s41598-020-69967-z
Hany Abdalla, Amanda M de Mestre, Shebl E Salem. Efficacy of ovulation synchronization with timed artificial insemination in treatment of follicular cysts in dairy cows. Theriogenology. 2020 May 21;154:171-180. doi: 10.1016/j.theriogenology.2020.05.029
Campbell MLH, Peachey L, Callan L, Wathes DC, de Mestre AM. Cyclical cervical function in the mare involves remodelling of collagen content, which is correlated with modification of oestrogen receptor 1 abundance. Anim Reprod Sci. 2019 Nov;210:106192. doi: 10.1016/j.anireprosci.2019.106192.
AM de Mestre, BV Rose, YM Chang, DC Wathes, KLP Verheyen. Multivariable analysis to determine risk factors associated with early pregnancy loss in thoroughbred broodmares, Theriogenology, 2019 Jan 15;124:18-23. doi: 10.1016/j.theriogenology.2018.10.008.
Read JE, Cabrera-Sharp V, Offord V, Mirczuk SM, Allen SP, Fowkes RC, de Mestre AM. Dynamic changes in gene expression and signalling during trophoblast development in the horse. Reproduction. 2018 Jul 10. pii: REP-18-0270. doi: 10.1530/REP-18-0270
Jordan E Read, Victoria Cabrera-Sharp, Phoebe Kitscha, Judith E Cartwright, Peter J King, Rob C Fowkes and Amanda M de Mestre. Glial Cells Missing 1 regulates equine Chorionic Gonadotrophin beta subunit via binding to the proximal promoter. Front. Endocrinology, 26 April 2018, 9: 195 https://doi.org/10.3389/fendo.2018.00195
Timpson, A; de Mestre, AM; Elliott, J; Harris, PA; Cheng, Z; Mirczuk, S M; Callan, L; Rainbow, L; Menzies-Gow, NJ. Seasonal and dietary influences on adipose tissue and systemic gene expression in control and previously laminitic ponies. Journal of Equine Veterinary Science, 2018, Volume 69, October 2018, Pages 84-95
ROSE BV, FIRTH M, MORRIS B, ROACH JM, WATHES DC, VERHEYEN KLP, DE MESTRE AM. Descriptive study of current therapeutic practices, clinical reproductive findings and incidence of pregnancy loss in intensively managed thoroughbred mares. Anim Reprod Sci. 2018 Jan;188:74-84.
CAMPBELL MLH, HAMPSHIRE D, HAMSTEAD L, ROSE B, SMITH KC, DE MESTRE AM The effects of intrauterine infusion of peanut oil on endometrial health, salivary cortisol and interovulatory period in mares. Theriogenology, 2017, 2017 Oct 15;102:116-125.
ALEKSIC D, BLASCHKE L, MIßBACH S, HÄNSKE J, WEIß W, HANDLER J, ZIMMERMANN W, CABRERA-SHARP V, READ JE, DE MESTRE AM, O'RIORDAN R, MOORE T, KAMMERER R. Convergent evolution of pregnancy-specific glycoproteins in the human and horse. Reproduction. 2016 Jun 8.
B.V. ROSE, V. CABRERA-SHARP, M.J. FIRTH, F.E. BARRELET, S. BATE, I.J. CAMERON, J.R. CRABTREE, J. CROWHURST, A.J. MCGLADDERY, H. NEAL, J. PYNN, O.D. PYNN, C. SMITH, Z. WISE, K.L.P. VERHEYEN, D.C. WATHES, A.M. DE MESTRE A method for isolating and culturing placental cells from failed early equine pregnancies. Placenta, Volume 38, February 2016, Pages 107–111.
CABRERA-SHARP V, READ JE, RICHARDSON S, KOWALSKI AA, ANTCZAK DF, CARTWRIGHT JE, MUKHERJEE A, DE MESTRE AM. SMAD1/5 signaling in the early equine placenta regulates trophoblast differentiation and chorionic gonadotropin secretion. Endocrinology. 2014 Aug;155(8):3054-64.
ROSE, B., FIRTH, M., MORRIS, B., NICHOLSON, C., VERHEYEN, K., WATHES, D.C. AND DE MESTRE, A.M. (2014), Incidence and Risk Factors Associated with Early Pregnancy Loss in Thoroughbreds. Equine Veterinary Journal, 46: 16. doi: 10.1111/evj.12323_35.
ACKERMAN WE 4TH, CARTER AM, DE MESTRE AM, GOLOS TG, JESCHKE U, KUSAKABE K, LAURENT LC, PARAST MM, ROBERTS RM, ROBINSON JM, RUTHERFORD J, SOMA H, TAKIZAWA T, UI-TEI K, LASH GE. IFPA Meeting 2012 Workshop Report I: comparative placentation and animal models, advanced techniques in placental histopathology, human pluripotent stem cells as a model for trophoblast differentiation. Placenta. 2013 Mar;34 Suppl:S3-5.
ANTCZAK, DF, DE MESTRE, AM, WILSHER S AND ALLEN WR. The Equine Endometrial Cup Reaction: A Feto-maternal Signal of Significance. Annual Review of Animal Biosciences, 2013, Vol. 1419.
DE MESTRE A. Reproductive failure in horses: identifying the problem. Vet Rec. 2013 Jan 12;172(2):42.
CRABTREE, J.R., CHANG, Y., AND, DE MESTRE A.M. (2012). Clinical presentation, treatment and possible causes of persistent endometrial cups illustrated by two cases. Equine Veterinary Education. 24(5):251-259.
ACKERMAN WE 4TH, BULMER JN, CARTER AM, CHAILLET JR, CHAMLEY L, CHEN CP, CHUONG EB, COLEMAN SJ, COLLET GP, CROY BA, DE MESTRE AM, DICKINSON H, DUCRAY J, ENDERS AC, FOGARTY NM, GAUSTER M, GOLOS T, HAIDER S, HEAZELL AE, HOLLAND OJ, HUPPERTZ B, HUSEBEKK A, JOHN RM, JOHNSEN GM, JONES CJ, KALIONIS B, KÖNIG J, LORENZON AR, MOFFETT A, MOREIRA DE MELLO JC, NUZZO AM, PARHAM P, PAROLINI O, PETROFF MG, PIDOUX G, RAMÍREZ-PINILLA MP, ROBINSON WP, ROLFO A, SADOVSKY Y, SOMA H, SOUTHCOMBE JH, TILBURGS T, LASH GE. (2012). IFPA Meeting 2011 workshop report III: Placental immunology; epigenetic and microRNA-dependent gene regulation; comparative placentation; trophoblast differentiation; stem cells. Placenta. 33 Suppl:S15-22. PubMed ID 22154501.
ROBBIN M.G., WAGNER B., NORONHA L.E., ANTCZAK D.F. AND DE MESTRE A.M. (2011). Subpopulations of equine blood lymphocyte expressing regulatory T cell markers. Vet Immunol Immunopathol 140:90-101 PubMed ID 21208665.
DE MESTRE AM., ANTCZAK, DF., AND ALLEN, WR. (2010). 'Equine Chorionic Gonadotropin' in Equine Reproduction, 2nd edition, A. McKinnon, E Squires, W. Vaala, D. Varner, Blackwell Publishing