Professor David Brodbelt
Department: Pathobiology & Population Sciences
Campus: Hawkshead
Research Groups: Antimicrobial Resistance, IRLFS (Research Programme), Cardiovascular and Renal Biology, CPCS (Research Programme)
Research Centres: Veterinary Epidemiology, Economics and Public Health
Dave Brodbelt is a Professor of Evidence based Veterinary Medicine at the Royal Veterinary College.
Dave Brodbelt graduated from the Cambridge Vet School in 1993 and undertook a residency in Veterinary Anaesthesia there. In 1998 he gained the RCVS Diploma in Veterinary Anaesthesia and became a Diplomate of the European College of Veterinary Anaesthesia and Analgesia. He then went into private practice for 4 years prior to undertaking an Epidemiology PhD based at the Epidemiology Unit of the Animal Health Trust / Royal Veterinary College looking at anaesthetic complications in veterinary practice (CEPSAF). Since then he has worked at the RVC within the Veterinary Epidemiology, Economics and Public Health (VEEPH) Group, Department of Pathobiology and Populations Sciences, focused primarily on companion animal epidemiology. He is involved in teaching epidemiology, statistics and EBVM to undergraduates and postgraduates. His research interests centre on companion animal epidemiology and research derived from electronic health records.
He is co-project leader of VetCompass, tthe RVC based companion animal surveillance programme that works with a large group of collaborating first opinion practices surveying disease trends in veterinary practice. He is chair of the VeNom Coding Group, a member of the APHA led Small Animal Expert Group (SAEG) and is currently the Senior Vice President of SVEPM, the Society for Veterinary Epidemiology and Preventive Medicine.
His main interests are companion animal epidemiology and practice based research. He is co-project leader for VetCompass, with Dr Dan O'Neill, Noel Kennedy and Prof David Church, the RVC led primary practice electronic health record project (www.rvc.ac.uk/VetCompass) that collects clinical data from veterinary practice management systems (PMS). He is a member of the VeNom Coding Group (www.venomcoding.org) that maintains standard clinical terminology for use in veterinary medicine and represents the VeNom Coding Group within the VetXML Consortium (www.vetxml.org). He is involved in a number of clinical research projects within the RVC working with colleagues in the QMHA.
In Veterinary Anaesthesia, following on from his PhD, his research interest continues to centre on perioperative morbid and mortal complications. His PhD thesis is available as a PDF below.
BRODBELT, D.C. (2006) The Confidential Enquiry into Perioperative Small Animal Fatalities. PhD Thesis, Royal Veterinary College, University of London.
ORCID ID orcid.org/0000-0001-5628-4194
2024
O'Neill DG, Williams A, Brodbelt DC, Church DB, Hedley J. Conformation-associated health in pet rabbits in the UK: A VetCompass cohort study. Vet Rec. 2024 Jul 8:e4396. doi: 10.1002/vetr.4396. Epub ahead of print. PMID: 38978404.
Pegram C, Diaz-Ordaz K, Brodbelt DC, Chang YM, Hall JL, Church DB, O'Neill DG. Later-age neutering causes lower risk of early-onset urinary incontinence than early neutering-a VetCompass target trial emulation study. PLoS One. 2024 Jul 3;19(7):e0305526. doi: 10.1371/journal.pone.0305526. PMID: 38959183.
Teng KT, Brodbelt DC, Church DB, O'Neill DG. Life tables of annual life expectancy and risk factors for mortality in cats in the UK. J Feline Med Surg. 2024 May;26(5):1098612X241234556. doi: 10.1177/1098612X241234556. PMID: 38714312.
O'Neill DG, Komutrattananon R, Church DB, Hartley AN, Brodbelt DC. The epidemiology of tick infestation in dog breeds in the UK. J Small Anim Pract. 2024 Apr 23. doi: 10.1111/jsap.13727. Epub ahead of print. PMID: 38653546.
Pegram C, Diaz-Ordaz K, Brodbelt DC, Chang YM, von Hekkel AF, Wu CH, Church DB, O'Neill DG. Target Trial Emulation: Does surgical versus non-surgical management of cranial cruciate ligament rupture in dogs cause different outcomes? Prev Vet Med. 2024 Mar 4;226:106165. doi: 10.1016/j.prevetmed.2024.106165. Epub ahead of print. PMID: 38503655.
O'Neill DG, Taffinder JL, Brodbelt DC, Baldrey V. Demography, commonly diagnosed disorders and mortality of guinea pigs under primary veterinary care in the UK in 2019-A VetCompass study. PLoS One. 2024 Mar 27;19(3):e0299464. doi: 10.1371/journal.pone.0299464. PMID: 38536813; PMCID: PMC10971687.
Jackson MA, Burn CC, Hedley J, Brodbelt DC, O'Neill DG. Dental disease in companion rabbits under UK primary veterinary care: Frequency and risk factors. Vet Rec. 2024 Mar 4:e3993. doi: 10.1002/vetr.3993. Epub ahead of print. PMID: 38439116.
Dale F, Brodbelt DC, West G, Church DB, Lee YH, O'Neill DG. Demography, common disorders and mortality of Shih Tzu dogs under primary veterinary care in the UK. Canine Med Genet. 2024 Jan 24;11(1):2. doi: 10.1186/s40575-023-00135-y. PMID: 38263229.
Engdahl KS, Brodbelt DC, Cameron C, Church DB, O'Neill DG. English Cocker Spaniels under primary veterinary care in the UK: disorder predispositions and protections. Canine Med Genet. 2024 Jan 18;11(1):1. doi: 10.1186/s40575-023-00136-x. PMID: 38233914; PMCID: PMC10795400.
2023
O'Neill DG, Engdahl KS, Leach A, Packer RMA, Church DB, Brodbelt DC. Is it now time to iron out the wrinkles? Health of Shar Pei dogs under primary veterinary care in the UK. Canine Med Genet. 2023 Dec 14;10(1):11. doi: 10.1186/s40575-023-00134-z. PMID: 38093396.
Allen SE, O'Neill DG, Cardwell JM, Verheyen KLP, Brodbelt DC. A study of the impact of the COVID-19 pandemic on equine veterinary care in the UK. Vet Rec Open. 2023 Nov 2;10(2):e74. doi: 10.1002/vro2.74. PMID: 37927814; PMCID: PMC10622737.
Kung U P, Brodbelt D. A review of human dog-bite injuries in Kitui South subcounty, Kenya (2017-2021). Vet Rec Open. 2023 Oct 9;10(2):e72. doi: 10.1002/vro2.72. PMID: 37822591; PMCID: PMC10562654.
Taylor C, Belin E, Brodbelt D, Klaasen HLBM, Catchpole B. Exploration of the potential utility of the luciferase immunoprecipitation system (LIPS) assay for the detection of anti-leptospira antibodies in dogs. Vet Immunol Immunopathol. 2023 Oct 6;264:110661. doi: 10.1016/j.vetimm.2023.110661. Epub ahead of print. PMID: 37827091.
Pegram C, Diaz-Ordaz K, Brodbelt DC, Chang YM, Tayler S, Allerton F, Prisk L, Church DB, O'Neill DG. Target trial emulation: Do antimicrobials or gastrointestinal nutraceuticals prescribed at first presentation for acute diarrhoea cause a better clinical outcome in dogs under primary veterinary care in the UK? PLoS One. 2023 Oct 4;18(10):e0291057. doi: 10.1371/journal.pone.0291057. PMID: 37792702; PMCID: PMC10550114.
O'Neill DG, McMillan KM, Church DB, Brodbelt DC. Dog breeds and conformations in the UK in 2019: VetCompass canine demography and some consequent welfare implications. PLoS One. 2023 Jul 26;18(7):e0288081. doi: 10.1371/journal.pone.0288081. PMID: 37494312; PMCID: PMC10370710.
O'Neill DG, Edmunds GL, Urquhart-Gilmore J, Church DB, Rutherford L, Smalley MJ, Brodbelt DC. Dog breeds and conformations predisposed to osteosarcoma in the UK: a VetCompass study. Canine Med Genet. 2023 Jun 27;10(1):8. doi: 10.1186/s40575-023-00131-2. PMID: 37365662; PMCID: PMC10294386.
Varney D, O’Neill D, O’Neill M, Church D, Stell A, Beck S, Smalley, M, Brodbelt DC. Epidemiology of mammary tumours in bitches under veterinary care in the UK in 2016. Vet Rec. 2023;e3054. https://doi.org/10.1002/vetr.3054
O'Neill DG, Skipper AM, Barrett K, Church DB, Packer RMA, Brodbelt DC. Demography, common disorders and mortality of Boxer dogs under primary veterinary care in the UK. Canine Med Genet. 2023 Jun 1;10(1):6. doi: 10.1186/s40575-023-00129-w. PMID: 37259166
Engdahl KS, Brodbelt DC, Cameron C, Church DB, Hedhammar Å, O'Neill DG. Demography and disorders of English Cocker Spaniels under primary veterinary care in the UK. Canine Med Genet. 2023 May 19;10(1):4. doi: 10.1186/s40575-023-00128-x. PMID: 37202773.
Pickard Price P, Stell A, O'Neill D, Church D, Brodbelt D. Epidemiology and risk factors for mammary tumours in female cats. J Small Anim Pract. 2023 Apr 3. doi: 10.1111/jsap.13598. Epub ahead of print. PMID: 37012055.
Heeley AM, Brodbelt DC, O'Neill DG, Church DB, Davison LJ. Assessment of glucocorticoid and antibiotic exposure as risk factors for diabetes mellitus in selected dog breeds attending UK primary-care clinics. Vet Rec. 2023 Apr 2:e2785. doi: 10.1002/vetr.2785. Epub ahead of print. PMID: 37004211.
Edmunds G, Beck S, Kale KU, Spasic I, O'Neill D, Brodbelt D, Smalley MJ. Associations Between Dog Breed and Clinical Features of Mammary Epithelial Neoplasia in Bitches: an Epidemiological Study of Submissions to a Single Diagnostic Pathology Centre Between 2008-2021. J Mammary Gland Biol Neoplasia. 2023 Mar 24;28(1):6. doi: 10.1007/s10911-023-09531-3. PMID: 36961631; PMCID: PMC10039094.
O'Neill DG, Blenkarn A, Brodbelt DC, Church DB, Freeman A. Periodontal disease in cats under primary veterinary care in the UK: frequency and risk factors. J Feline Med Surg. 2023 Mar;25(3):1098612X231158154. doi: 10.1177/1098612X231158154. PMID: 36912667.
Elkholly D, Fraser A, Booth R, O'Neill D, Mateus A, Brunton L, Brodbelt D. Antimicrobial usage in farm animal practices in the UK: A mixed-methods approach. Prev Vet Med. 2023 Feb 10;213:105870. doi: 10.1016/j.prevetmed.2023.105870. Epub ahead of print. PMID: 36841042.
O'Neill DG, Gunn-Moore D, Sorrell S, McAuslan H, Church DB, Pegram C, Brodbelt DC. Commonly diagnosed disorders in domestic cats in the UK and their associations with sex and age. J Feline Med Surg. 2023 Feb;25(2):1098612X231155016. doi: 10.1177/1098612X231155016. PMID: 36852509.
Pegram C, Brodbelt DC, Diaz-Ordaz K, Chang Y, von Hekkel AF, Church DB, O'Neill DG. Risk factors for unilateral cranial cruciate ligament rupture diagnosis and for clinical management in dogs under primary veterinary care in the UK. Vet J. 2023 Jan 25:105952. doi: 10.1016/j.tvjl.2023.105952. Epub ahead of print. PMID: 36708945.
2022
Allen SE, Verheyen KLP, O'Neill DG, Brodbelt DC. Use of antimicrobials licensed for systemic administration in UK equine practice. Equine Vet J. 2022 Oct 5. doi: 10.1111/evj.13878. Epub ahead of print. PMID: 36199158.
O'Neill DG, Khoo JSP, Brodbelt DC, Church DB, Pegram C, Geddes RF. Frequency, breed predispositions and other demographic risk factors for diagnosis of hypothyroidism in dogs under primary veterinary care in the UK. Canine Med Genet. 2022 Oct 10;9(1):11. doi: 10.1186/s40575-022-00123-8. PMID: 36217196
Shoop-Worrall SJ, O'Neill DG, Viscasillas J, Brodbelt DC. Mortality related to general anaesthesia and sedation in dogs under UK primary veterinary care. Vet Anaesth Analg. 2022 Jun 30:S1467-2987(22)00101-5. doi: 10.1016/j.vaa.2022.03.006. Epub ahead of print. PMID: 35985925
Taylor C, O'Neill DG, Catchpole B, Brodbelt DC. Leptospirosis vaccination in dogs attending UK primary care practices: vaccine uptake and factors associated with administration. BMC Vet Res. 2022 Jul 22;18(1):285. doi: 10.1186/s12917-022-03382-6. PMID: 35864518; PMCID: PMC9303131.
O'Neill DG, Rowe D, Brodbelt DC, Pegram C, Hendricks A. Ironing out the wrinkles and folds in the epidemiology of skin fold dermatitis in dog breeds in the UK. Sci Rep. 2022 Jul 6;12(1):10553. doi: 10.1038/s41598-022-14483-5. PMID: 35794173; PMCID: PMC9259571.
O'Neill DG, Kim K, Brodbelt DC, Church DB, Pegram C, Baldrey V. Demography, disorders and mortality of pet hamsters under primary veterinary care in the United Kingdom in 2016. J Small Anim Pract. 2022 Jun 22. doi: 10.1111/jsap.13527. Epub ahead of print. PMID: 35732354.
O'Neill DG, Skipper A, Packer RMA, Lacey C, Brodbelt DC, Church DB, Pegram C. English Bulldogs in the UK: a VetCompass study of their disorder predispositions and protections. Canine Med Genet. 2022 Jun 15;9(1):5. doi: 10.1186/s40575-022-00118-5.
O'Neill DG, Sahota J, Brodbelt DC, Church DB, Packer RMA, Pegram C. (2022) Health of Pug dogs in the UK: disorder predispositions and protections. Canine Med Genet, May 18;9(1):4.
Teng KT, Brodbelt DC, Pegram C, Church DB, O'Neill DG. (2022) Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom. Sci Rep. 2022 Apr 28;12(1):6415. doi: 10.1038/s41598-022-10341-6.
Craven, A.J., Pegram, C., Packer, R.M.A., Brodbelt, D.C., Neill, D.G. (2022) Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care. PLoS ONE, 2022, 17(1 January), e0261139.
O'Neill, D.G., Yin, Y., Pont, R.T., Brodbelt, D.C., Pegram, C., Mustikka, M. (2022) Breed and conformational predispositions for prolapsed nictitating membrane gland (PNMG) in dogs in the UK: A VetCompass study. PLoS ONE 2022, 17(1 January), e02605
Beeston D, Humm K, Church DB, Brodbelt D, O'Neill DG. (2022) Occurrence and clinical management of urethral obstruction in male cats under primary veterinary care in the United Kingdom in 2016. J Vet Intern Med. 2022 Feb 24. doi: 10.1111/jvim.16389.
2021
O'Neill DG, Packer RMA, Francis P, Church DB, Brodbelt DC, Pegram C. (2021) French Bulldogs differ to other dogs in the UK in propensity for many common disorders: a VetCompass study. Canine Med Genet. 2021 Dec 16;8(1):13. doi: 10.1186
Tompson AC, Mateus ALP, Brodbelt DC, Chandler CIR. (2021) Understanding Antibiotic Use in Companion Animals: A Literature Review Identifying Avenues for Future Efforts. Front Vet Sci. 2021 Oct 8;8:719547.
Schofield I, Brodbelt DC, Niessen SJM, Church DB, Geddes RF, O'Neill DG. (2021) Frequency and risk factors for naturally occurring Cushing's syndrome in dogs attending UK primary-care practices. J Small Anim Pract. 2021 Dec 8.
O'Neill DG, Lee YH, Brodbelt DC, Church DB, Pegram C, Halfacree Z. (2021) Reporting the epidemiology of aural haematoma in dogs and proposing a novel aetiopathogenetic pathway. Sci Rep. 2021 Nov 9;11(1).
Taylor C, Brodbelt DC, Dobson B, Catchpole B, O'Neill DG, Stevens KB. (2021) Spatio-temporal distribution and agroecological factors associated with canine leptospirosis in Great Britain. Prev Vet Med. 2021 Aug;193:105407.
O'Neill DG, Volk AV, Soares T, Church DB, Brodbelt DC, Pegram C. (2021) Frequency and predisposing factors for canine otitis externa in the UK - a primary veterinary care epidemiological view. Canine Med Genet. 2021 Sep 7;8(1):7.
O'Neill DG, Mitchell CE, Humphrey J, Church DB, Brodbelt DC, Pegram C (2021) Epidemiology of periodontal disease in dogs in the UK primary-care veterinary setting. J Small Anim Pract. 2021 Aug 9.
Pegram C, Woolley C, Brodbelt DC, Church DB, O'Neill DG. (2021) Disorder predispositions and protections of Labrador Retrievers in the UK. Sci Rep. 2021 Jul 14;11(1):13988
Schofield I, Brodbelt DC, Kennedy N, Niessen SJM, Church DB, Geddes RF, O'Neill DG. (2021) Machine-learning based prediction of Cushing's syndrome in dogs attending UK primary-care veterinary practice. Sci Rep. 2021 Apr 27;11(1):9035.
Taylor C, O'Neill DG, Catchpole B, Brodbelt DC. (2021) Incidence and demographic risk factors for leptospirosis in dogs in the UK. Vet Rec. 2021 May 31:e512. doi: 10.1002/vetr.512.
O'Neill, D. G., Brodbelt, D. C., Keddy, A., Church, D. B. & Sanchez, R. F. (2021) Keratoconjunctivitis sicca in dogs under primary veterinary care in the UK: an epidemiological study. J Small Anim Pract, https://onlinelibrary.wiley.com/doi/full/10.1111/jsap.13382
Pegram C, Gray C, Packer RMA, Richards Y, Church DB, Brodbelt DC, O'Neill DG.(2021) Proportion and risk factors for death by euthanasia in dogs in the UK. Sci Rep. 2021 May 4;11(1):9145. doi: 10.1038/s41598-021-88342-0.
Pegram C, Raffan E, White E, Ashworth AH, Brodbelt DC, Church DB, O'Neill DG. (2021) Frequency, breed predisposition and demographic risk factors for overweight status in dogs in the UK. J Small Anim Pract. 2021 Mar 23.
Brodbelt D. (2021) Breaking new ground in antimicrobial stewardship in companion animal veterinary practice. Nat Commun. 2021 Apr 27;12(1):2445. doi: 10.1038/s41467-021-22542-0.
Schofield I, Brodbelt DC, Kennedy N, Niessen SJM, Church DB, Geddes RF, O'Neill DG. (2021) Machine-learning based prediction of Cushing's syndrome in dogs attending UK primary-care veterinary practice. Sci Rep. 2021 Apr 27;11(1):9035.
Dórea FC, Vergne T, Brennan M, van Schaik G, Barrett D, Carmo LP, Robinson PA, Brodbelt DC, McIntyre KM (2021) SVEPM 2020 - Resilience and community support in the first year of the COVID-19 pandemic: The Society for Veterinary Epidemiology and Preventive Medicine Annual Conference, extraordinarily held online. Prev Vet Med. 2021 Apr 28
Economu L, Stell A, O'Neill DG, Schofield I, Stevens K, Brodbelt D (2021) Incidence and risk factors for feline lymphoma in UK primary-care practice. J Small Anim Pract. 2020 Dec 15. doi: 10.1111/jsap.13266
Schofield I, Woolhead V, Johnson A, Brodbelt DC, Church DB, O'Neill DG (2021) Hypoadrenocorticism in dogs under UK primary veterinary care: frequency, clinical approaches and risk factors. J Small Anim Pract. 2021 Feb 8. doi: 10.1111/jsap.13285
O'Neill DG, James H, Brodbelt DC, Church DB, Pegram C. (2021) Prevalence of commonly diagnosed disorders in UK dogs under primary veterinary care: results and applications. BMC Vet Res. 2021 Feb 17;17(1):69. doi: 10.1186/s12917-021-02775-3.
O'Neill DG, Hendricks A, Phillips JA, Brodbelt DC, Church DB, Loeffler A (2021) Non-neoplastic anal sac disorders in UK dogs: Epidemiology and management aspects of a research-neglected syndrome. Vet Rec. 2021 Mar 1:e203. doi: 10.1002/vetr.203.
Edmunds GL, Smalley MJ, Beck S, Errington RJ, Gould S, Winter H, Brodbelt DC, O'Neill DG. (2021) Dog breeds and body conformations with predisposition to osteosarcoma in the UK: a case-control study. Canine Med Genet. 2021 Mar 10;8(1):2. doi: 10.1186/s40575-021-00100-7.
2020
Tompson A, Chandler C, Mateus, A, O’Neill D, Chang YM, Brodbelt D (2020) What drives antimicrobial prescribing for companion animals? A mixed-methods study of UK veterinary clinics. Pre Vet Med, 5 Aug, https://doi.org/10.1016/j.prevetmed.2020.105117
O'Neill DG, Pegram C, Crocker P, Brodbelt DC, Church DB, Packer RMA. (2020) Unravelling the health status of brachycephalic dogs in the UK using multivariable analysis. Sci Rep. 2020 Oct 14;10(1):17251.
O'Neill DG, Phillipps SA, Egan JR, Brodbelt D, Church DB, Volk HA. (2020) Epidemiology of recurrent seizure disorders and epilepsy in cats under primary veterinary care in the United Kingdom. J Vet Intern Med. 2020 Sep 25. doi: 10.1111/jvim.15881.
Schofield I, Brodbelt DC, Niessen SJM, Church DB, Geddes RF, Kennedy N, O'Neill DG. (2020) Development and internal validation of a prediction tool to aid the diagnosis of Cushing's syndrome in dogs attending primary-care practice. J Vet Intern Med. 2020 Sep 16. doi: 10.1111/jvim.15851.
Pegram C, Wonham K, Brodbelt DC, Church DB & O’Neill DG (2020) Staffordshire Bull Terriers in the UK: their disorder predispositions and protections. Canine Medicine and Genetics volume 7, Article number: 13
Elkholly DA, Brodbelt DC, Church DB, Pelligand L, Mwacalimba K, Wright AK, O'Neill DG (2020) Side Effects to Systemic Glucocorticoid Therapy in Dogs Under Primary Veterinary Care in the UK. Front Vet Sci. doi: 10.3389/fvets.2020.00515.. 2020 Aug 14;7:515.
Kathrani A, Church DB, Brodbelt DC, Pegram C, O'Neil DG. (2020) The use of hydrolysed diets for vomiting and/or diarrhoea in cats in primary veterinary practice. J Small Anim Pract. 2020 Sep 7. doi: 10.1111/jsap.13214.
Radulescu SM, Humm K, Eramanis LM, Volk HA, Church DB, Brodbelt D, O'Neill DG. (2020) Vestibular disease in dogs under UK primary veterinary care: Epidemiology and clinical management. J Vet Intern Med. 2020 Aug 10. doi: 10.1111/jvim.15869
Pegram CL, Rutherford L, Corah C, Church DB, Brodbelt DC, O'Neill DG. (2020) Clinical management of lipomas in dogs under primary care in the UK.Vet Rec. 2020 Jul 13: vetrec-2019-105804. doi: 10.1136/vr.105804.
Heeley, A.M., O'Neill, D.G., Davison, L.J., Church, D.B., Corless, E.K. and Brodbelt, D.C. (2020) Diabetes mellitus in dogs attending UK primary-care practices: frequency, risk factors and survival. Canine Medicine and Genetics, 7(1), 6
O'Neill DG, Turgoose E, Church DB, Brodbelt DC, Hendricks A: (2020) Juvenile-onset and adult-onset demodicosis in dogs in the UK: prevalence and breed associations. Journal of Small Animal Practice 2020,61(1):32-41.
O'Neill DG, Packer RMA, Lobb M, Church DB, Brodbelt DC, Pegram C.(2020) Demography and commonly recorded clinical conditions of Chihuahuas under primary veterinary care in the UK in 2016. BMC Vet Res. 2020 Feb 12;16(1):42. doi: 10.1186/s12917-020-2258-1.
O'Neill DG, Brodbelt DC, Hodge R, Church DB, Meeson RL: Epidemiology and clinical management of elbow joint disease in dogs under primary veterinary care in the UK. Canine Medicine and Genetics 2020,7(1):1.
2019
Schofield I, O'Neill DG, Brodbelt DC, Church DB, Geddes RF, Niessen SJM. (2019) Development and evaluation of a health-related quality-of-life tool for dogs with Cushing's syndrome. J Vet Intern Med. 2019 Nov;33(6):2595-2604. doi: 10.1111/jvim.15639.
Schofield I, Stevens KB, Pittaway C, O'Neill DG, Fecht D, Dobson JM, Brodbelt DC (2019) Geographic distribution and environmental risk factors of lymphoma in dogs under primary-care in the UK. J Small Anim Pract. 2019 Dec;60(12):746-754. doi: 10.1111/jsap.13075.
O'Neill DG, Craven HC, Brodbelt DC, Church DB, Hedley J. (2019) Morbidity and mortality of domestic rabbits (Oryctolagus cuniculus) under primary veterinary care in England. Vet Rec. 2019 Oct 8. pii: vetrec-2019-105592. doi: 10.1136/vr.105592.
Pegram C, Brodbelt DC, Church DB, Hall J, Owen L, Chang YM, O'Neill DG. (2019) Associations between neutering and early-onset urinary incontinence in UK bitches under primary veterinary care. J Small Anim Pract. 2019 Oct 7. doi: 10.1111/jsap.13072.
O'Neill DG, Turgoose E, Church DB, Brodbelt DC, Hendricks A. (2019) Juvenile-onset and adult-onset demodicosis in dogs in the UK: prevalence and breed associations. J Small Anim Pract. 2019 Oct 4. doi: 10.1111/jsap.13067.
Schofield I, Brodbelt DC, Wilson ARL, Niessen S, Church D, O'Neill D. (2019) Survival analysis of 219 dogs with hyperadrenocorticism attending primary care practice in England. Vet Rec. 2019 Sep 20. pii: vetrec-2018-105159. doi: 10.1136/vr.105159
O'Neill DG, Romans C, Brodbelt DC, Church DB, Cerná P, Gunn-Moore DA. (2019) Persian cats under first opinion veterinary care in the UK: demography, mortality and disorders. Nature Sci Rep. 2019 Sep 17;9(1):12952. doi: 10.1038/s41598-019-49317-4.
O'Neill DG, Ballantyne ZF, Hendricks A, Church DB, Brodbelt DC, Pegram C. (2019) West Highland White Terriers under primary veterinary care in the UK in 2016: demography, mortality and disorders. Canine Genet Epidemiol. 2019 Sep 3;6:7. doi: 10.1186/s40575-019-0075-2.
Summers, J, O’Neill D, Church D, Sargan D, Collins L, Brodbelt, D (2019) Health-related welfare prioritisation of canine disorders using electronic health records in primary care practice in the UK. BMC Veterinary Research, 15:163. doi.org/10.1186/s12917-019-1902-0.
Kennedy N, Brodbelt D, Church D O’Neill D (2019) Detecting false-positive disease references in veterinary clinical notes without manual annotations. npj Digital Medicine volume 2, Article number: 33 (2019).
O'Neill DG, Butcher C, Church DB, Brodbelt DC, Gough AG. (2019) Miniature Schnauzers under primary veterinary care in the UK in 2013: demography, mortality and disorders. Canine Genet Epidemiol. 2019 Feb 15;6:1. doi: 10.1186/s40575-019-0069-0.
Elkholly DA, O'Neill D, Wright AK, Mwacalimba K, Nolan LS, Pavlock A, Pelligand L, Church D, Brodbelt DC. (2019) Systemic glucocorticoid usage in dogs under primary veterinary care in the UK: prevalence and risk factors. Vet Rec. 2019 May 10. pii: vetrec-2018-105220. doi: 10.1136/vr.105220.
Pegram C, O'Neill DG, Church DB, Hall J, Owen L, Brodbelt DC. (2019) Spaying and urinary incontinence in bitches under UK primary veterinary care: a case-control study. J Small Anim Pract. 2019 Apr 29. doi: 10.1111/jsap.13014.
Conroy, M C; Brodbelt, D C; O'Neill, D G; Chang, Y M; Elliott, J. (2019) Chronic kidney disease in cats attending primary care practice in the UK: a VetCompass study. Vet Rec. 2019 Apr 27;184(17):526
O'Neill DG, Butcher C, Church DB, Brodbelt DC, Gough AG. (2019) Miniature Schnauzers under primary veterinary care in the UK in 2013: demography, mortality and disorders. Canine Genet Epidemiol. 2019 Feb 15;6:1. doi: 10.1186/s40575-019-0069-0.
O'Neill DG, O'Sullivan AM, Manson EA, Church DB, McGreevy PD, Boag AK, Brodbelt DC. (2019) Canine dystocia in 50 UK first-opinion emergency care veterinary practices: clinical management and outcomes. Vet Rec. 2019 Feb 4. pii: vetrec-2018-104944. doi: 10.1136/vr.104944.
Mattin M, Brodbelt D, Church D, Boswood A (2019) Factors associated with disease progression in dogs with presumed preclinical degenerative mitral valve disease attending primary-care veterinary practices in the UK. JVIM.2Mar;33(2):445-454. doi: 10.1111/jvim.15390.
Hall, J. L., Owen, L., Riddell, A., Church, D. B., Brodbelt, D. C. & O’Neill, D. G. (2019). Urinary incontinence in male dogs under primary veterinary care in England: prevalence and risk factors. Journal of Small Animal Practice. Feb;60(2):86-95. doi.org/10.1111/jsap.12951
Conroy M, O'Neill D, Boag A, Church D, Brodbelt D. (2019) Epidemiology of road traffic accidents in cats attending emergency-care practices in the UK. J Small Anim Pract. 60(3):146-152. doi: 10.1111/jsap.12941.
2018.
Mattin M, Boswood A, Church D, Brodbelt D (2018) Prognostic factors in dogs with presumed degenerative mitral valve disease attending primary care veterinary practices in the UK. JVIM, Mar;33(2):432-444. doi: 10.1111/jvim.15251.
Conroy M, Chang YM, Brodbelt D, Elliott J. (2018) Survival after diagnosis of hypertension in cats attending primary care practice in the United Kingdom. J Vet Intern Med. 2018 Oct 13. doi: 10.1111/jvim.15307.
McGreevy PD, Wilson BJ, Mansfield CS, Brodbelt DC, Church DB, Dhand N, Soares Magalhães RJ, O'Neill DG. (2018) Labrador retrievers under primary veterinary care in the UK: demography, mortality and disorders. Canine Genet Epidemiol. 2018 Oct 22;5:8. doi: 10.1186/s40575-018-0064-x
O'Neill, D G; Baral, L; Church, D B; Brodbelt, D C; Packer, R M A.
Demography and disorders of the French Bulldog population under primary veterinary care in the UK in 2013.
Canine Genetics and Epidemiology, 5;3 (2018)
Harris GL, Brodbelt D, Church D, Humm K, McGreevy PD, Thomson PC, O'Neill D. (2018) Epidemiology, clinical management, and outcomes of dogs involved in road traffic accidents in the United Kingdom (2009-2014). J Vet Emerg Crit Care (San Antonio). 2018 Mar;28(2):140-148. doi: 10.1111/vec.12704. Epub 2018 Mar 6.
O'Neill DG, Corah CH, Church DB, Brodbelt DC, Rutherford L. (2018) Lipoma in dogs under primary veterinary care in the UK: prevalence and breed associations. Canine Genet Epidemiol. 2018 Sep 27;5:9. doi: 10.1186/s40575-018-0065-9
Renwick SM, Renwick AI, Brodbelt DC, Ferguson J, Abreu H. (2018) I
He is involved in teaching undergraduate and postgraduate students. He teaches evidence-based veterinary medicine (EBVM), epidemiology and statistics to BVetMed veterinary undergraduates, BSc and BScVN students and the Clinical Residents (SCTS) at the RVC. He is the Research Skills Module leader for the MSc programmes in Veterinary Epidemiology, One Health and Wild Animal Biology and Health and contributes to the Distance Learning MSc in Veterinary Epidemiology and Public Health at the RVC.
He is a Fellow of the Higher Education Academy.
His clinical interests centre around Anaesthesia where he is involved in the research project supervision of the Senior Clinical Traning Scholars (SCTS) in veterinary anaesthesia as well as in other companion animal disciplines.
He is a member and chair of the VeNom Coding Group, that has developed and maintains the standard veterinary terminology, the VeNom Codes (www.venomcoding.org).
He is a member of the VetXML consortium (www.vetxml.org) that is defining and driving electronic communication standards to facilitate communication and exchange data across the profession.
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Antimicrobial usage in farm animal veterinary practice in the UK: A mixed-methods approach (In Progress)
People: David Brodbelt, Dan O'Neill, Richard Booth
Vet Compass Project Type: Farm Animal
The aims of this study are to estimate current antimicrobial usage in Farm Veterinary Practice and investigate the intrinsic factors and extrinsic factors associated with farm veterinarian decision-making when prescribing antimicrobials as well as exploring the drivers behind farmers' decision when using antimicrobials.
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Are lop-eared rabbits more predisposed to dental and ear diseases than erect-eared rabbits? (Complete)
People: Charlotte Burn, David Brodbelt, Joanna Hedley, Dan O'Neill
Vet Compass Project Type: Rabbit
We aim to deepen understanding of the animal welfare impacts of dental and ear disease in rabbits, and to identify breed related risk factors for these. We plan to use the new information to improve rabbit welfare by raising awareness of any dental and ear health implications from selecting for rabbit with extreme morphology.
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BVetMed RP2 Research Projects (In Progress)
People: Dan O'Neill, David Brodbelt
Vet Compass Project Type: Dog, Cat, Small Mammal, Exotic
All BVetMed veterinary undergraduates at the RVC are required to complete a formal piece of research (named Research Project 2 “RP2”) as part of their route towards gaining a veterinary degree. This project is a Level 7 body of work that is at the level of a master’s project. VetCompass supports students to undertake these RP2 projects at the RVC. The Kennel Club Charitable Trust has supported several VetCompass RP2s annually on topics related to canine health.
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Canine leptospirosis: improving diagnostics and understanding epidemiology in UK dogs
This project aims to explore the epidemiology of canine leptospirosis in the UK by identifying spatial patterns of disease, diagnosis risk factors and incidence of disease. Alongside this work is being undertaken to explore vaccine usage and vaccine adverse events. Additionally, a novel serological assay with potentialp DIVA ability is being explored.
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Canine leptospirosis: Improving diagnostics and understanding of the epidemiology of disease in UK dogs (In Progress)
People: Brian Catchpole, David Brodbelt
Vet Compass Project Type: Dog
The project, co-sponsored by BBSRC and MSD, aims to improve the diagnostics of Leptospirosis in canids.
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CatScan
The CatScan study was set up to investigate the prevalence of hypertrophic cardiomyopathy (HCM) in the general cat population by screening apparently healthy cats in rehoming centres.
Hypertrophic cardiomyopathy is a thickening (hypertrophy) of the muscles of the wall of the left ventricle of the heart causing the heart to be less able to relax between contractions. In some cases, this can lead to an increase in pressure in the left atrium which then enlarges. The increase in pressure in the left atrium causes back pressure in the blood vessels of the lungs and a fluid build up in the lungs. In severe cases, a blood clot can sometimes form within the enlarged left atrium.
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Chronic Kidney Disease in Cats Attending UK Practices (Complete)
People: Ruby Chang, David Brodbelt, Jonathan Elliott
Vet Compass Project Type: Cat
This project, funded by Ceva, estimated the
prevalence of, andrisk-factors for chronic kidney disease in cats attending VetCompass-participating veterinary practices in the United Kingdom. As a second objective, the prevalence of hypertensionan current practices for measuring and treating hypertension were explored. -
Current Usage of Antimicrobials in UK Cats and Dogs (Complete)
People: Dan O'Neill, David Church, David Brodbelt
Vet Compass Project Type: Cat, Dog
This research characterised and quantified antimicrobial use in cats and dogs attending a large group of UK veterinary practices, in order to establish companion animal antimicrobial prescribing behaviour.
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Diabetes mellitus and antibiotics – exploring the use of antibiotics as a risk factor for the disease (Complete)
People: Lucy Davison, David Brodbelt, Dan O'Neill
Vet Compass Project Type: Dog
The project aims to report the incidence of canine diabetes mellitus cases diagnosed in primary care veterinary practices in the United Kingdom and to describe and explore systemic antibiotic usage prior to dogs developing diabetes mellitus.
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Disease Surveillance in Cavalier King Charles Spaniels and Chow Chows in the UK (Complete)
People: David Church, David Brodbelt, Dan O'Neill
Vet Compass Project Type: Dog
This project explored the frequency of disorders recorded in Cavalier King Charles Spaniels and Chow Chows attending primary-care veterinary practices in the UK. The project also looked at the feasibility of linking Kennel Club pedigree data with VetCompass data.
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Do lop-eared rabbits have more dental and aural disease than erect-eared rabbits?
Initial evidence has shown that rabbits with artificially selected extreme morphological traits of lop ears and brachycephaly experience reduced welfare through a higher prevalence of painful ear and teeth problems, a cause for concern as lops and dwarves are the most popular pet rabbit breeds in the UK. This study aims to determine the prevalence of these diseases in UK pet rabbits using VetCompass data that represents approximately 30% of UK practices.
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Dogs Trust Canine Welfare Grant Project: Evidence-Based Prioritisation of Canine Inherited Diseases (Complete)
People: David Church, David Brodbelt, Dan O'Neill
Vet Compass Project Type: Dog
This study aims to create an evidence-based prioritisation list of inherited health disorders to underpin reforms of canine health and welfare.
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Earlier Onset Urinary Incontinence in the Bitch and its Association with Neutering
Funded by BSAVA PetSavers, this project aims to evaluate major risk factors for development of urinary incontinence in bitches. In particular, it will explore the association between neutering and age at time of neutering with onset of early incontinence.
The project will provide relevant and reliable evidence that can support a more universal approach from veterinary surgeons and provide advice to dog owners regarding neutering.
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Earlier Onset Urinary Incontinence in the Bitch and its Association with Neutering (Complete)
People: Dan O'Neill, David Brodbelt
Vet Compass Project Type: Dog
Funded by BSAVA PetSavers, this project aims to evaluate major risk factors for development of urinary incontinence in bitches. In particular, it will explore the association between neutering and age at time of neutering with onset of early incontinence.
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Epidemiology of Disorders Reported in Cats and Dogs Attending General Practice in England (Complete)
People: Dan O'Neill, David Church, David Brodbelt
Vet Compass Project Type: Cat, Dog
This project reports on the most common disorders of dogs and cats attending veterinary practice in the UK, their longevity and mortality, and risk factors for chronic kidney disease in dogs.
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Equine VetCompass: Guiding Evidence-Based Equine Healthcare (Complete)
People: Kristien Verheyen, David Brodbelt
Vet Compass Project Type: Horse
Funded by the RVC’s Mellon Fund for Equine Research and RCVS Knowledge, this project aims to estimate the prevalence of, and determine risk factors for, the most common disorders affecting horses attended to by veterinary practitioners in the UK.
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Improved Stewardship to Protect Veterinary Antimicrobial Usage in UK Cats and Dogs
This study aims to identify and promote effective antimicrobial stewardship interventions in UK first-opinion companion animal practice. Our objectives are to benchmark current antimicrobial usage in dogs and cats, develop and implement a range of antimicrobial stewardship interventions, evaluate the impact of these interventions, and promote widespread adoption of the most effective interventions across the UK.
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Improved Stewardship to Protect Veterinary Antimicrobial Usage in UK Cats and Dogs (In Progress)
People: David Brodbelt, Dan O'Neill, Sian Frosini, Noel Kennedy, David Church
Vet Compass Project Type: Dog, Cat, Small Animal
Funded by the Petplan Charitable Trust, this project aims to identify and promote effective and practical antimicrobial stewardship interventions for widespread adoption in veterinary practice.
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Man’s Best Friend: Risk Factors for Canine Cancer (Complete)
People: David Brodbelt
Vet Compass Project Type: Dog
This study looked at risk factors for the major canine cancers, including environmental factors which may be markers for disease in co-habiting humans.
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Morris Animal Foundation Canine Cancer Epidemiology Research Programme (In progress)
People: David Brodbelt, Dan O'Neill, Sandra Guillen, Collette Taylor
Vet Compass Project Type: Dog
This project aims to explore the frequency of different cancers and factors associated with these cancers in dogs from the Golden Retriever Lifetime Study cohort. Alongside this, VetCompass health data will be examined to explore cancer frequency and risk factors in both Golden Retrievers and the wider, UK primary-practice attending population.
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RCVS VetCompass Equine Pandemic Project (Complete)
People: Sarah Allen, Dan O'Neill, Jackie Cardwell, Kristien Verheyen, David Brodbelt
Vet Compass Project Type: Horse
The COVID-19 pandemic presents a serious challenge for the customer-facing veterinary profession. To ensure minimal disruption to essential veterinary services, new COVID-mitigated working protocols were quickly implemented, however, little is known about the impact of the pandemic on equine veterinary care in the UK. The aim of this project was to describe equine veterinary activity before and during the pandemic and explore the contribution of telemedicine to case management.
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Re-Inventing Diagnosis and Management of Canine Hyperadrenocorticism (Complete)
People: Dan O'Neill, David Brodbelt, David Church
Vet Compass Project Type: Dog
This project, funded by Dechra, aims to determine better methods for the earlier detection and monitoring of hyperadrenocorticism in dogs. More effective diagnosis and monitoring may result in improved quality of life.
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The Effectiveness of Antimicrobials for the Treatment of Canine Pyoderma in the UK (Complete)
People: Anke Hendricks, David Brodbelt
Vet Compass Project Type: Dog
This study aimed to estimate the frequency of canine pyoderma and its treatment and to evaluate risk factors for treatment relapse and failure in UK primary and referral veterinary practice.
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UFAW/RVC Companion Animal Genetic Health and Welfare Research (Complete)
People: David Brodbelt, Dan O'Neill
Vet Compass Project Type: Cat, Dog, Horse
This project developed evidence-based recommendations on breed-related health and welfare problems in companion animals.
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Use of Systemic Antimicrobials in UK Equine Practice (Complete)
People: Kristien Verheyen, Dan O'Neill, David Brodbelt
Vet Compass Project Type: Horse
The project aims to investigate the use of systemic antimicrobials in UK equine practice using anonymised veterinary electronic patient record data.
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VetCompass eClinical Trials (In Progress)
People: Dan O'Neill, David Brodbelt, Ruby Chang, Noel Kennedy
Vet Compass Project Type: Dog
The study aims to develop innovative statistical approaches to veterinary electronic patient records to evaluate the effectiveness of clinical interventions in dogs.
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VetCompass eClinical Trials (VETs) – Generating Interventional Evidence from Observational Data
The study aims to develop innovative statistical approaches to veterinary electronic patient records to evaluate the effectiveness of clinical interventions in dogs.
This project aims to develop and apply novel causal inference methods that evaluate real world interventions via routinely collected veterinary EPRs. These methods will be applied to VetCompass data to provide real world inference for some key interventions.
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VetCompass Project
VetCompass is a welfare-focussed epidemiological research project that shares anonymised clinical data from veterinary practices to investigate the frequency and nature of companion animal health problems.
Modern veterinary medicine has access to increasingly effective tools for diagnosis and treatment; yet many animals still continue to suffer from disorders that might be reduced or avoided if risks were better understood and measured.